THE SCIENCE
OF NAD+
Decades of research. One essential molecule. Found in every living cell, NAD+ is the molecule your body uses to produce energy, repair DNA, and regulate the processes that determine how well, and how long you age.
↓50%
Decline in NAD+ levels between your 20s and 60s
100+
Peer-reviewed clinical trials on NAD+ in humans
Every cell
In your body depends on NAD+ to produce energy
THE SCIENCE
Dr Mark Jinks: The Science of NAD+
NAD+ (nicotinamide adenine dinucleotide) is a vital coenzyme found in every cell. It helps convert food into energy (ATP), fuels cellular repair, and supports key processes like metabolism, DNA repair, and circadian rhythms.
As we age, NAD+ levels decline significantly, often dropping by more than half by our 60s. This loss is linked to reduced cellular function, increased inflammation, and other signs of aging.
Maintaining healthy NAD+ levels is a central focus of modern longevity science.
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What NAD+ does inside your cells
Energy production
NAD+ is the central electron carrier in cellular respiration, the process inside your mitochondria that converts nutrients into ATP, the energy currency powering every cell.
DNA repair
NAD+ activates sirtuins and PARP enzymes, two of the body's primary DNA repair mechanisms. This helps correct cellular damage over time, reducing the risk of dysfunction that accelerates ageing.
Longevity signalling
NAD+ activates sirtuins, a family of proteins linked to lifespan regulation and cellular stress resistance. Higher NAD+ levels help your cells respond more effectively to damage and environmental stress.
Immune regulation
NAD+ supports immune cell function and helps regulate inflammation at a cellular level. Maintaining adequate levels helps your body mount effective responses without tipping into chronic, low-grade inflammation.
Circadian rhythm
NAD+ levels naturally rise and fall in sync with your body clock, helping regulate sleep-wake cycles and metabolic timing. Supporting NAD+ helps keep this rhythm consistent, improving sleep quality and daytime energy.
Cognitive function
NAD+ fuels the energy-intensive demands of brain cells and supports the repair of neurons over time. This underpins sharper focus, better memory retention, and more consistent mental performance.
Made to the highest standard.
Our NAD+ formulation is dosed to the levels used in peer-reviewed clinical trials, manufactured in certified facilities, and third-party tested for purity and potency.
Our NAD+ formulation is dosed to the levels used in peer-reviewed clinical trials, manufactured in a certified facilities, and third-party tested for purity and potency.
Third-party tested
Every batch is independently tested by accredited laboratories for purity, potency, and the absence of heavy metals, pathogens, and contaminants before it reaches you.
GMP certified facility
Our products are manufactured in a Good Manufacturing Practice certified facilities, meeting the same regulatory standards required for pharmaceutical-grade production.
Full label transparency
No proprietary blends, no hidden ingredients. Every component and its exact quantity is listed on the label, so you always know precisely what you're putting into your body.
Clinically informed dosing
Our dosing is based on the concentrations used in peer-reviewed clinical research, not arbitrary amounts. You get what the science actually supports.
Physician reviewed
Our formulations and protocols have been reviewed by medical professionals to ensure they meet clinical safety standards and are appropriate for at-home use.
THE MEDICAL TEAM
Backed by science, powered by people
Developed with guidance from our in-house medical team, every NAD+ 4u product is shaped by clinical oversight, ingredient research, and quality testing.
Head of Nursing
Maddie Booth
Leads customer-facing nursing support and helps answer questions, including first-time pen setup.
Chief Medical Officer
Dr Mark Jinks
Oversees clinical protocols to ensure the highest standards of safety, governance and medical integrity.
Developed with guidance from our in-house medical team, every NAD+ 4u product is shaped by clinical oversight, ingredient research, and quality testing.
Peer-reviewed science
NAD+ is one of the fastest-growing areas in longevity research. These studies highlight strong peer-reviewed evidence, from clinical trials to systematic reviews supporting these claims.
Wellness references
NAD+ for increasing energy, reducing free radicals, anti-ageing
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Clinical applications
NAD+ for neurodegenerative diseases, cardiovascular risk factors, inflammatory conditions, hypoxic/chemotoxic damages, mental health
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